diff --git a/.changes/remove-autostart-nsis-uninstall.md b/.changes/remove-autostart-nsis-uninstall.md
new file mode 100644
index 000000000..c79dc83c4
--- /dev/null
+++ b/.changes/remove-autostart-nsis-uninstall.md
@@ -0,0 +1,5 @@
+---
+"tauri-bundler": patch:bug
+---
+
+Remove the autostart plugin registry entry when the app is uninstalled (NSIS only).
diff --git a/crates/tauri-bundler/src/bundle/windows/nsis/installer.nsi b/crates/tauri-bundler/src/bundle/windows/nsis/installer.nsi
index 8ed4adc0b..556aed8e6 100644
--- a/crates/tauri-bundler/src/bundle/windows/nsis/installer.nsi
+++ b/crates/tauri-bundler/src/bundle/windows/nsis/installer.nsi
@@ -835,6 +835,16 @@ Section Uninstall
     DeleteRegKey HKCU "${UNINSTKEY}"
   !endif
 
+  ; Removes the Autostart entry for ${PRODUCTNAME} from the HKCU Run key if it exists.
+  ; This ensures the program does not launch automatically after uninstallation if it exists.
+  ; If it doesn't exist, it does nothing.
+  ; We do this when not updating (to preserve the registry value on updates)
+  ; and when the installation is for the current user only - as it is difficult to delete registry values for other users or for the local machine
+  ${If} $UpdateMode <> 1
+  ${AndIf} "${INSTALLMODE}" == "currentUser"
+    DeleteRegValue HKCU "Software\Microsoft\Windows\CurrentVersion\Run" "${PRODUCTNAME}"
+  ${EndIf}
+
   ; Delete app data if the checkbox is selected
   ; and if not updating
   ${If} $DeleteAppDataCheckboxState = 1